Artesunate 60 mg + Sodium bicarbonate 1 ml amp. + +Sodium chloride 5 ml amp

Artesunate 60 mg + Sodium bicarbonate 1 ml amp. + +Sodium chloride 5 ml amp

Last updated on

14 Feb 2019

Product added on

14 Feb 2019

We are

looking for distributors

Space Required

400 sq ft

Investment Required

Rs 1 Lac- Rs 5 Lac

Brand

Alleviate Pharmaceuticals

Product Description

Artesunate (INN) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection rtesunate is a water-soluble hemisuccinate derivative of artemisinin. It is unstable in neutral solution and the injectable formulation must be prepared immediately before use in 5% (w/v) sodium bicarbonate solution to produce the salt sodium artesunate. After parenteral administration, it is rapidly hydrolysed to the active metabolite dihydroartemisinin. The oral formulation is probably hydrolysed completely before entering the systemic circulation. Artesunate has been reported to clear fever in patients with severe falciparum malaria 16-25 hours after parenteral administration.

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